BD Veritor System Bedienungsanleitung Seite 17

Strain Reactivity with Influenza A and B Viruses
The BD Veritor System for Rapid Detection of Flu A+B test was evaluated using a panel of influenza strains. Each strain was
diluted and tested in triplicate until a point where not all of the replicates were positive. The dilution prior to that is provided in
the table below as a minimal detected concentration. All influenza A strains showed positive Flu A test results and negative
Flu B test results. Conversely, all of the influenza B strains showed positive Flu B test results and negative Flu A test results.
Although this test has been shown to detect novel avian influenza A (H7N9) and H3N2v cultured viruses the performance
characteristics of this device with clinical specimens that are positive for novel avian influenza A (H7N9) and H3N2v influenza
viruses has not been established. The BD Veritor System Flu A+B assay can distinguish between influenza A and B viruses,
but it cannot differentiate influenza A subtypes.
Strain
A/Brisbane/59/2007
A/California/7/2009
A/Denver/1/57
A/FM/1/47
A/Fujian-Gulou/1896/2009
A/Mal/302/54
A/New Caledonia/20/1999
A/New Jersey/8/76
A/NWS/33
A/PR/8/34
A/Solomon Island/03/2006
A/Washington/24/2012
A/Weiss/43
A/WS/33
A/Aichi/2/68
A/Brisbane/10/2007
A/California/02/2014
A/Hong Kong/8/68
A/Moscow/10/99
A/Perth/16/2009
A/Port Chalmers/1/73
A/Switzerland/9715293/2013
A/Texas/50/2012
A/Wisconsin/67/2005
A/Victoria/3/75
A/Indiana/08/2011
A/Indiana/10/2011
A/Kansas/13/2009
A/Minnesota/11/2010
A/Pennsylvania/14/2010
A/West Virginia/06/2011
A/Anhui/01/2005
A/Vietnam/1203/2004
A/Northern Pintail/Washington/40964/2014
A/Pheasant/NewJersey/1355/1998
A/Gyrfalcon/Washington/41088-6/2014
A/Mallard/Netherlands/12/2000
A/Anhui/1/2013
A/Chicken/HongKong/G9/1997
*Values taken from preceding Analytical Limit of Detection Table
a. EID = 50% Egg Infectious Dose
50
b. TCID = 50% Tissue Culture Infectious Dose
50
c. CEID = 50% Chicken Embryo Infectious Dose
50
d. HA = Hemagglutination Assay
Subtype Minimal Detected Concentration
H1N1 3.3 x 10
H1N1 5.0 x 10
H1N1 4.45 x 10
H1N1 7.91 x 10
H1N1 4.5 x 10
H1N1 2.22 x 10
H1N1 2.5 x 10
H1N1 1.58 x 10
H1N1 1.58 x 10
H1N1 6.31 x 10
H1N1 2.5 x 10
H1N1 3.16 x 10
H1N1 7.03 x 10
H1N1 7.91 x 10
H3N2 7.91 x 10
H3N2 7.27 x 10
H3N2 1.45 x 10
H3N2 8.89 x 10
H3N2 5.8 x 10
H3N2 1.0 x 10
H3N2 3.95 x 10
H3N2 3.25 x 10
H3N2 1.75 x 10
H3N2 2.5 x 10
H3N2 3.11 x 10
H3N2v 1 x 10
H3N2v 7.9 x 10
H3N2v 1.0 x 10
H3N2v 7.9 x 10
H3N2v 1.26 x 10
H3N2v 7.9 x 10
H5N1 0.512 HA
H5N1 0.512 HA
H5N2 6.28 x 10
H5N2 0.256 HA
H5N8 1.98 x 10
H7N7 0.256 HA
H7N9 5.42 x 10
H9N2 1.024 HA
17
2 TCID /mL*
50
TCID /mL*
3
50
4 CEID /mL
50
4 CEID /mL
50
5 CEID /mL
50
5 CEID /mL
50
3 TCID /mL
50
3 CEID /mL
50
CEID /mL
4
50
2 TCID /mL
50
3 TCID /mL
50
4 EID /mL
50
6 CEID /mL
50
2 CEID /mL
50
3 CEID /mL
50
TCID /mL*
2
50
2 TCID /mL
50
4 CEID /mL
50
6 TCID /mL
50
6 TCID /mL
50
4 CEID /mL
50
2 TCID /mL
50
TCID /mL
3
50
5 TCID /mL
50
3 TCID /mL*
50
4 TCID /mL
50
6 CEID /mL
50
3 TCID /mL
50
5 CEID /mL
50
CEID /mL
6
50
3 TCID /mL
50
5 EID /mL
50
6 EID /mL
50
6 CEID /mL*
50