Actim Partus 1ngeni Gebrauchsanweisung Seite 67

Table 1.
CORRELATION BETWEEN CLINICAL OUTCOME AND CLINICAL DATA
WITHIN 7 DAYS.
Outcome phIGFBP-1
median (µg/l)
≤7 days 15.0
>7 days 4.0
p-value 0.011*
Table 3.
RELATIVE RISK OF PRETERM DELIVERY ACCORDING TO QUANTITATIVE
ACTIM PARTUS 1NGENI CATEGORIES.
phIGFPB-1 Delivery Delivery
category (ng/ml) ≤ 7 days ≤ 14 days
≤2 - -
2.1-9.9 5.3* 1.5
10.0-49.9 5.8* 2.1
50.0-249.9 7.7* 4.2*
≥ 250 13.5** 11.1***
Relative risk compared to phIGFBP-1 ≤2 ng/ml.
z-statistics significance: *P<0.05, **P<0.01, ***P < 0.001
Cervical lenght p-value
median (mm)
15.0 -0,421*
30.0 0.076
0.001* *p ≤0.05
Delivery Delivery Delivery
< 30 wks < 34 wks < 37 wks
- - -
0.5 1.4 1.6*
5.8* 3.3** 2.4***
11.5** 4.1** 2.4***
20.3*** 8.7*** 3.9***
Table 2.
PRETERM DELIVERY RATES IN SYMPTOMATIC WOMEN ACCORDING TO
QUANTITATIVE ACTIM PARTUS 1NGENI CATEGORIES.
phIGFPB-1 Delivery Delivery
category (ng/ml) ≤ 7 days ≤ 14 days
≤2 0.7% 2.6%
2.1-9.9 3.8% 3.8%
10.0-49.9 4.1% 5.4%
50.0-249.9 5.4% 10.8%
≥ 250 9.5% 28.6%
Table 4.
SPONTANEOUS PRETERM DELIVERY RATES IN SYMPTOMATIC WOMEN
ACCORDING TO QUANTITATIVE ACTIM PARTUS 1NGENI CATEGORIES.
phIGFPB-1 Delivery Delivery
category (ng/ml) ≤ 7 days ≤ 14 days
≤2 0.5% 3.4%
2.1-9.9 2.9% 2.9%
10.0-49.9 4.9% 7.3%
50.0-249.9 7.7% 15.4%
≥ 250 11.1% 27.8%
Delivery Delivery Delivery
< 30 wks < 34 wks < 37 wks
0.7% 3.3% 15.7%
0% 4.5% 24.8%
4.1% 10.8% 37.8%
8.1% 13.5% 37.8%
14.3% 28.6% 61.9%
Delivery Delivery Delivery
< 30 wks < 34 wks < 37 wks
1.0% 3.9% 19.5%
0% 5.7% 28.6%
4.9% 9.8% 39.0%
11.5% 19.2% 42.3%
16.7% 27.8% 61.1%