Sartorius Sartocon Slice Self Contained Gebrauchsanleitung Seite 19

The backpressure on the filtrate side is defined as:
Backpressure on the filtrate side (P
is higher than the retentate pressure.
P
P
This should especially be taken into consideration if hydrostatic conditions
(e.g., tank height and pipe diameter) are influencing the backpressure.
t
Note that there is a difference between the transmembrane pressure (TMP)
TMP = [(P
and the differential pressure
P
The following must be noted:
Monitor TFF conditions during filtration. When filtering under static
conditions (dead-end filtration), the filtration performance of the cassettes
is rapidly reduced (see chapter "6 Filtration", page 23).
Components of a Complete TFF System
Air filter
PE4
Retentate
Bag
Feed
HV-4
Sartocheck quick connection
®
Fig. 10: Drawing: TFF system
Instructions for Use Sartocon
> P
perm ret
= P – P
back perm ret
Ensure that these values are not exceeded.
+ P ) : 2] – P
feed ret perm
= P – P
diff feed ret
PE 2
HV-2
Holder
PE 1
P-1
HV-1
Quick connection Sterile connection
Slice Self Contained | Sartocube
®
Installation
) occurs when the permeate pressure
back
PE 3
Permeate
HV-3
Flushing
Outlet 1
Outlet 2
Self Contained
®
Air filter
PE 5
Bag
19