Rinsing Cassettes; Integrity Test; Information About Complaints - Sartorius Stedim Biotech Sartocon Slice Installationsanleitung

12 Installation
4.3.1

Rinsing Cassettes

Before using a cassette, it is recommended to rinse it with 10 liters of deionized
water, buffers or physiological saline solution.
Set the inlet pressure (P
t t
feed
Limit the retentate outlet enough so that the ratio of permeate flow to retentate
t t
flow is 1:1.
Reduce the permeate and retentate flows.
t t
After approx. one-third of the rinsing agent has been used, stop rinsing for
t t
15 minutes and then continue to rinse again.
4.3.2

Integrity Test

Each cassette is fully tested at Sartorius. It is therefore recommended that no other
integrity test be carried out on-site.

4.4 Information about Complaints

If you would like to send cassettes to Sartorius Stedim Biotech for review, please
ensure the following:
− that the cassettes have been completely cleaned;
− that the cassettes have been disinfected;
− that the cassettes are provided with the following information:
− the medium that was filtered using the cassettes;
− any errors that were observed;
− the operating parameters in use at the time of filtration (pressure settings,
operating time, process cycles, cleaning conditions, operating temperature);
− cleaning method used;
− disinfecting agent used.
For further information, please request the return form from our applications
technician.
) to 1 bar.