Personal Safety - Axis-Shield RPR Bedienungsanleitung

Specimens should be equilibrated to room temperature (15 to 30 °C) before testing begins.
Storage of specimens in self-defrosting freezers is not recommended.
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Personal safety

Caution: Handle Axis-Shield RPR with care; potentially infectious material. This product includes
materials prepared from human serum or plasma that has been tested and found to be non reactive
for antibody to HIV-1 and HIV-2, HIV-1 RNA or HIV-1 Ag, antibody to hepatitis C virus (HCV) as well
as for hepatitis B surface antigen (HBsAg). However, as it is not possible to offer complete assurance
that infectious agents are not present, all materials of human origin should be handled as though they
might contain potentially infectious agents.
The Antigen suspension and the controls contain sodium azide as a preservative.
WARNING
EUH032 –
PREVENTION
WARNING
Antigen
RESPONSE
Suspension
P305+351+338 –
P337+313 –
Positive
Control
EUH032 -
Negative
Control
Use disposable gloves and handle all materials used in the assay including samples, waste solution,
reaction trays and pipettes, cautiously as though capable of transmitting infectious agents e.g.
according to NCCLS M29-A2. Consult a physician immediately in the event that contaminated
materials are ingested or come in contact with open lacerations, lesions, or other breaks in the skin.
* NCCLS M29-A2 Protection of Laboratory Workers from Occupationally Acquired infections
(second edition, approved guideline).
Spills of potentially infectious material should be cleaned up immediately; e.g. with absorbent paper
tissue and the contaminated area should be decontaminated with, for example, 0.5 % freshly prepared
sodium hypochlorite (1 : 10) dilution of 5 % sodium hypochlorite (household bleach) before work
continues.
Sodium hypochlorite should not be used on acid-containing spill unless the spill-area is first
wiped dry.
Materials used to clean spills, including gloves, should be disposed of as potentially biohazardous
waste e.g. in a biohazard waste container.
Disinfect and/or autoclave the solutions or wastes containing biological samples before disposing of
them according to local regulations.
Samples and reagents of human origin, as well as contaminated materials, disposables, neutralized
acids and other waste materials must be decontaminated before disposal, either by:
–
by immersion in a freshly prepared 0.5 % of sodium hypochlorite for 30 minutes (1 volume of
5 % sodium hypochlorite for 10 volumes of contaminated fluid or water). Neutralize
(chemically) liquid wastes that contain acid before adding sodium hypochlorite
–
or by autoclaving at 121 °C for 60 minutes.
Autoclaving is the best method to inactivate HIV and HBV.
Do not autoclave materials or solutions containing sodium hypochlorite.
Chemicals should be handled in accordance with Good Laboratory Practice and disposed of according
to local instructions.
H319 –
Causes serious eye irritation.
Contact with acids liberates very toxic gases.
P264 –
Wash hands thoroughly after handling.
P280 –
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if
present and easy to do. Continue rinsing.
If eye irritation persists: get medical advice attention.
Contact with acids liberates very toxic gases.
Cleaning & decontamination
Disposal & destruction
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