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Clinic6 Freezpen CL-FP-00 Gebrauchsanweisung Seite 7

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Contraindications :
Unstable diabetes
Skin conditions, e.g. skin tumors, esanthema, open wounds,
solar hyperkeratosis
Unexplained, suspicious liver spots and moles
Cancer tissues and malignant tumors
The contraindications related to temporary conditions :
Infections accompanied by fever
Acute chemotherapy or radiotherapy from four weeks before
beginning the therapy to four weeks after finishing the therapy
Pregnancy or breastfeeding
Cold intolerance
Vascular insufficiency
Reduce possible side-effects.
Although cryotherapy is a relatively low-risk procedure, some side
effects may occur as a result of the treatment. They include:
Permanent changes in pigmentation. Both hypopigmentation
(lightening of the skin) and hyperpigmentation (darkening of
the skin) may occur after cryotherapy. Both generally last a
few months, but can be longer lasting.
Sensory impairment. Though rare, damage to nerves is
possible, particularly in areas where these are positioned
closer to the surface of the skin, such as in the fingers, the
wrist, and the area behind the ear. Reports suggest effects will
disappear within several months.
Spattering of the cryogen during spraying, when the end
nozzle freezes. The innovation of Freezpen is the direct
application of nitrous oxide under high pressure (55 bar). This
high pressure jet may cause minor shards of frozen humidity
in the air, blown away in a circle of approximately 30cm. They
will thaw the moment they would eventually touch healthy
skin.
Hair loss. Hair follicles are easily damaged by cryosurgery and
permanent hair loss is not uncommon.
Pigmented spots. It is common use to not treat pigmented
spots in sunny seasons. Solar lentigines (SL) are flat brown
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